Investigators: Maja Edenius, PhD, Research Fellow, Chang-Yeol Yeo, PhD, Research Fellow
Funder(s): NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
The use of small molecules to manipulate metabolic function in vivo has emerged as an important new approach to therapy for a wide range of disease pathologies. The amino acid starvation response (AAR) is a signaling pathway that controls a variety metabolic and cytoprotective functions in response to the restriction of amino acid availability. In our preliminary...
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