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Jeffrey Bush
Department of Cell and Tissue Biology
University of California San Francisco School of Dentistry
Session Summary: The Bush lab studies signaling control of mammalian morphogenesis, which is of fundamental importance because birth defects are the leading cause of death for infants during the first year of life. The lab has made discoveries on how the EPH/EPHRIN signaling family regulates cell position and tissue shape in craniofacial development, has uncovered cellular mechanisms of tissue fusion in lip and secondary palate development, and more recently, has also focused on the early stages of trachea and esophagus morphogenesis. In this talk, Dr. Bush will share recent work on the fundamental aspects of craniofacial morphogenesis relating to structural craniofacial differences such as cleft lip and palate, and new models for syndromic craniofacial conditions.